Creatine Beta-Ketoglutarate

Creatine Beta-Ketoglutarate
Product Introduction:

CAS No.: 315669-78-4

Assay: ≥98.0%

Appearance: White crystalline powder

Molecular Formula: C₉H₁₅N₃O₇

Molecular Weight: 277.23

Storage: Store in a cool, dry, dark place, keep sealed

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Description
Technical Parameters

Shandong Changrui Biotech Co., Ltd. is one of the leading manufacturers and suppliers of creatine beta-ketoglutarate in China. Please feel free to wholesale bulk high purity creatine beta-ketoglutarate in stock here from our factory. All our raw materials are with high quality and competitive price. Contact us for pricelist.

 

Product Introduction

 

Creatine Beta-Ketoglutarate is a 1:1 ionically bonded complex of creatine and alpha-ketoglutarate (AKG). It offers dual-pathway support-combining energy production with metabolic function-and is specifically designed for pre-workout formulations and products supporting amino acid metabolism. Its core value lies in simultaneously delivering the ATP-regenerating capabilities of creatine and the Krebs cycle intermediate support of AKG; furthermore, with solubility levels falling between those of creatine monohydrate and highly soluble salts, it serves as a cost-effective raw material for brands developing metabolism-enhancing, complex creatine products.

 

Technical Specifications

 

Property

Specification

Appearance

White crystalline powder

Assay

98.0% min

AKG Content

52%-54%

Creatine Content

46%-48%

Loss on Drying

0.5% max

Residue on Ignition

0.1% max

Heavy Metals (as Pb)

10 PPM max

Arsenic (As)

0.5 PPM max

Lead (Pb)

2.0 PPM max

Mercury (Hg)

0.1 PPM max

Cadmium (Cd)

0.5 PPM max

Total Plate Count

1000 CFU/g max

Mold & Yeast

100 CFU/g max

E. coli

Negative

Salmonella

Negative

 

Health Benefits & Values   

01/

Energy for Explosive Workouts

Promotes intracellular phosphocreatine production to sustain power during short-duration, high-intensity explosive exercise.

02/

Eases Metabolic Burden From Heavy Training

Facilitates clearance of ammonia metabolites generated by strenuous exercise, relieving metabolic stress from repeated intense training cycles.

03/

Dual Nutrition for Fitness Formulations

Provides workout energy support alongside TCA-cycle intermediate nutrients, enabling finished products with combined energy and metabolic balance positioning.

04/

Ideal for Pre-Workout Supplement Use

Fits pre-training regimens for amateur and mid-level athletes with frequent intensive exercise schedules.

05/

Good Tolerance for Long-Term Supplementation

Both components naturally exist in human metabolism; this complex delivers mild physiological effects for long-term intake at recommended dosages.

Core Value in Formulation Development 

Streamline Bill-Of-Materials For Metabolic-Focused Pre-Workout Formulas

 

Combines creatine and alpha-ketoglutarate within one single raw material. Formulators can reduce separate-ingredient procurement for recipes targeting metabolic balance, simplifying overall formula architecture.

Fixed-Ratio Composition Supports Reproducible Formulation Outcomes

 

Stable 1:1 molar ratio delivers consistent AKG and creatine content (AKG 52-54 %, creatine 46-48 %). This tight compositional window supports predictable calculation for each serving's functional component loading.

Medium-Solubility Creates Practical Formulation Trade-Offs

 

Its ~11.5 g/L solubility sits between low-solubility monohydrate and high-solubility salt-type creatine derivatives. It performs well for dry powder-premix and semi-solid systems, yet is not suited for high-concentration transparent RTD beverage development.

Broad Compatibility For Multi-Ingredient Pre-Workout Blends

 

Shows favourable co-existence with beta-alanine, citrulline, caffeine, electrolyte salts and B-vitamin series, making it easy to integrate into complex multi-component pre-workout powder workflows.

End-Application Scenarios

Metabolism-Oriented Pre-Workout Powder Formulas (Core Track)

Dry-blend pre-workout powder lines focused on metabolic stress management for high-intensity training crowds.

Post-Exercise Recovery Sports-Nutrition Powders and Capsules

Powder and capsule finished goods targeting post-training recuperation, supporting muscle energy replenishment together with whole-body metabolic equilibrium maintenance.

High-Intensity Training Ammonia-Scavenging Supplement Lines

Creatine Beta-Ketoglutarate is specialised supplement portfolios for users undertaking frequent heavy-volume training.

Compound Multi-Functional Creatine Supplement Blends

Multi-ingredient dry premixes built to stand apart from commodity-grade monohydrate-only supplement offerings.

Premium Metabolism-Boosted Sports-Nutrition Product Lines

High-end supplement ranges adopting "metabolism-enhanced creatine" market positioning for fitness-oriented consumer groups.

 

Application Advantages and Market Positioning

Distinct Metabolic-Focused Niche Differentiator

Fills a unique market slot among creatine derivatives, combining muscle-energy provision with ammonia-homeostasis-related benefits. It differentiates itself from pure-performance-only or liquid-optimised creatine-salt competitors.

Target Audience For High-Volume Training Crowds

Specifically caters to brand and CMO partners developing supplement products for fitness enthusiasts and intermediate-level athletes exposed to recurring heavy training stress.

Complementary Positioning Within Full Creatine Ingredient Portfolio

Serves as a complementary option alongside high-solubility liquid-focused creatine salts and precision-solid-form anhydrous creatine, completing ingredient selection for multi-product sports-nutrition brand portfolios.

Good Fit For Mid-Tier Premium Pre-Workout Segment

Matches market demand for differentiated pre-workout ingredients that add metabolic-balance storytelling without requiring high-cost ultra-specialised raw-material specifications.

FAQ (Technical Q&A)

 

Q1: What is the core difference between this product and Creatine Monohydrate?

A: It is an ionic-bonded complex of creatine and AKG, providing both creatine and AKG; monohydrate provides only creatine.

Q2: What is the recommended dosage?

A: 2-5 g per serving (as complex) in pre-workout and sports nutrition powders. Specific dosage depends on target product claims and regulatory requirements.

Q3: What about the solubility?

A: Approximately 11.5 g/L at 25°C, higher than monohydrate but lower than creatine HCl.

Q4: Is it suitable for liquid formulations?

A: Stable in solid powder form, suitable for powders and semi-solid formulations. In aqueous solution, prepare fresh or store refrigerated.

Q5: What is the role of AKG?

A: AKG is a Krebs cycle intermediate that helps convert ammonia into glutamate, supporting metabolic balance.

Q6: How does Creatine Beta-Ketoglutarate differ from Creatine HCl and Creatine Nitrate?

A: It focuses on "energy + AKG metabolic support" for pre-workout and metabolism-enhanced formulas; Creatine HCl focuses on "room-temperature instant dissolution + stomach gentleness" for RTD and sensitive consumers; Creatine Nitrate focuses on "high solubility + NO vasodilation" for liquid formulations. Different positioning.

Q7: What about the dry stability?

A: Maintains stability for at least 1 year under room-temperature dry conditions, reducing creatinine formation during storage.

Q8: Can you customize premix blends?

A: Yes. Custom premix blends with other pre-workout or sports nutrition ingredients supported, with formulation development and compatibility testing.

Q9: Can it be used in pet nutrition?

A: Yes. It can be used in canine and feline sports recovery and metabolic support supplements.

Q10: What is the AKG source?

A: AKG is sourced from food-grade alpha-ketoglutaric acid, combined with creatine via ionic bonding to form a stable complex, compliant with food and dietary supplement regulations.

Q11: What applications is this product best suited for?

A: Pre-workout powders, sports nutrition capsules, ammonia metabolism support, and premium differentiated products.

 

 

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